IMPACT OF SUPEROVULATION AND IN VITRO FERTILIZATION ON LINE 1 COPY NUMBER AND TELOMERE LENGTH IN C57BL/6J MICE BLASTOCYSTS
نویسندگان
چکیده
Over 15 million babies have been conceived by IVF, yet debate about its safety to offspring continues. We hypothesized that superovulation and in vitro fertilization (IVF) promote genomic changes, including altered telomere length (TL) activation of the retrotransposon LINE-1 (L1), tested this hypothesis a mouse model.
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2021
ISSN: ['0015-0282', '1556-5653']
DOI: https://doi.org/10.1016/j.fertnstert.2021.07.465